US 12,478,620 B2
Cyano-substituted cyclic hydrazine derivative and application thereof
Wang Shen, Shanghai (CN); Pengfei Liu, Shanghai (CN); Rujun Bai, Shanghai (CN); Yufei Liu, Shanghai (CN); Qiuping Luo, Shanghai (CN); Pingbo Ke, Shanghai (CN); and Yanchuan Gong, Shanghai (CN)
Assigned to E-NITIATE BIOPHARMACEUTICALS (HANGZHOU) CO., LTD, Hangzhou (CN)
Appl. No. 17/642,567
Filed by E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd, Hangzhou (CN)
PCT Filed Jun. 11, 2020, PCT No. PCT/CN2020/095605
§ 371(c)(1), (2) Date Mar. 11, 2022,
PCT Pub. No. WO2021/051899, PCT Pub. Date Mar. 25, 2021.
Claims priority of application No. 201910872780.1 (CN), filed on Sep. 16, 2019.
Prior Publication US 2022/0339146 A1, Oct. 27, 2022
Int. Cl. A61K 31/4545 (2006.01); A61K 31/438 (2006.01); A61K 31/439 (2006.01); A61K 31/496 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); C07D 471/14 (2006.01); C07D 519/00 (2006.01)
CPC A61K 31/4545 (2013.01) [A61K 31/438 (2013.01); A61K 31/439 (2013.01); A61K 31/496 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07D 471/14 (2013.01); C07D 519/00 (2013.01)] 6 Claims
 
1. A cyano-substituted cyclic hydrazine derivative, wherein the cyclic hydrazine derivative is a compound represented by the following structural formula or a stereoisomer, geometric isomer, tautomer, racemate, hydrate, solvate, pharmaceutically acceptable salt, or prodrug thereof;

OG Complex Work Unit Chemistry