US 12,478,607 B2
Compounds useful for inhibiting BFL1 and their use in therapy
David A. Hildeman, Cincinnati, OH (US); Andrew Herr, Cincinnati, OH (US); Suhas G. Kallapur, Cincinnati, OH (US); Jarek Meller, Cincinnati, OH (US); and Alexander Thorman, Cincinnati, OH (US)
Assigned to Children's Hospital Medical Center, Cincinnati, OH (US)
Appl. No. 17/597,515
Filed by CHILDREN'S HOSPITAL MEDICAL CENTER, Cincinnati, OH (US)
PCT Filed Jul. 9, 2020, PCT No. PCT/US2020/070249
§ 371(c)(1), (2) Date Jan. 10, 2022,
PCT Pub. No. WO2021/007593, PCT Pub. Date Jan. 14, 2021.
Claims priority of provisional application 62/872,822, filed on Jul. 11, 2019.
Prior Publication US 2022/0249437 A1, Aug. 11, 2022
Int. Cl. A61K 31/382 (2006.01); A61K 31/353 (2006.01); A61K 47/69 (2017.01); A61P 31/04 (2006.01); A61P 35/00 (2006.01)
CPC A61K 31/382 (2013.01) [A61K 31/353 (2013.01); A61K 47/6913 (2017.08)] 12 Claims
 
1. A method for treating chorioamnionitis in a subject in need of such treatment, the method comprising administering to the subject compound 1.001:

OG Complex Work Unit Chemistry