US 12,478,562 B2
Dental restoration material composition
Hirotaka Horiguchi, Niigata (JP); and Tatsuya Kajikawa, Chiba (JP)
Assigned to KURARAY NORITAKE DENTAL INC., Kurashiki (JP)
Appl. No. 17/787,975
Filed by KURARAY NORITAKE DENTAL INC., Kurashiki (JP)
PCT Filed Dec. 24, 2020, PCT No. PCT/JP2020/048454
§ 371(c)(1), (2) Date Jun. 22, 2022,
PCT Pub. No. WO2021/132463, PCT Pub. Date Jul. 1, 2021.
Claims priority of application No. 2019-233577 (JP), filed on Dec. 24, 2019.
Prior Publication US 2023/0040426 A1, Feb. 9, 2023
Int. Cl. A61K 6/889 (2020.01); A61K 6/17 (2020.01); A61K 6/60 (2020.01); A61K 6/62 (2020.01); A61K 6/71 (2020.01); A61K 6/76 (2020.01); A61K 6/77 (2020.01); A61K 6/887 (2020.01)
CPC A61K 6/889 (2020.01) [A61K 6/17 (2020.01); A61K 6/60 (2020.01); A61K 6/62 (2020.01); A61K 6/71 (2020.01); A61K 6/76 (2020.01); A61K 6/77 (2020.01); A61K 6/887 (2020.01)] 13 Claims
 
1. A dental restoration material composition comprising:
a (meth)acrylic acid ester compound (A) having two or more (meth)acryloyloxy groups per molecule;
a mono(meth)acrylic acid ester compound (B);
a polymerization initiator (C); and
an organic-inorganic composite filler (D),
wherein the organic-inorganic composite filler (D) is an organic-inorganic composite filler that has an average particle diameter of 3 μm to 25 μm, and in which an inorganic filler having an average primary particle diameter of 0.5 μm or less is dispersed in an organic matrix,
wherein the organic-inorganic composite filler (D) is present in an amount of 30 to 75 mass % of a total amount of the dental restoration material composition, and
wherein the mono(meth)acrylic acid ester compound (B) comprises at least one selected from the group consisting of a mono(meth)acrylic acid ester compound (B-1) represented by formula (I), and a mono(meth)acrylic acid ester compound (B-2) represented by formula (II),

OG Complex Work Unit Chemistry
wherein R1 and R2 are each independently a group represented by formula (i) or a group represented by formula (ii), and X is an oxygen atom,

OG Complex Work Unit Chemistry
wherein R3 and R5 are each independently a divalent hydrocarbon group having 1 to 10 carbon atoms, R4 and R6 are each independently a hydrogen atom or a methyl group, and k and l are each independently an integer of 0 to 6.