US 12,478,468 B2
Replacement heart valve having improved preformed seal
Arnaud Humair, Mont-sur-Rolle (CH); Jean-Luc Hefti, Cheseaux-Noréaz (CH); and Stephane Delaloye, Buelach (CH)
Assigned to Symetis SA, Ecublens (CH)
Filed by Symetis SA, Ecublens (CH)
Filed on Sep. 3, 2021, as Appl. No. 17/466,431.
Claims priority of application No. 20194408 (EP), filed on Sep. 3, 2020.
Prior Publication US 2022/0061984 A1, Mar. 3, 2022
Int. Cl. A61F 2/24 (2006.01)
CPC A61F 2/2409 (2013.01) [A61F 2/2418 (2013.01); A61F 2/2412 (2013.01); A61F 2210/0014 (2013.01); A61F 2210/0085 (2013.01); A61F 2240/001 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A cardiac stent-valve for transcatheter delivery, the stent-valve being compressible to a compressed state for delivery, and expandable to an expanded state for implantation, the stent-valve comprising:
a stent with an axial inflow end and an axial outflow end,
a plurality of leaflets arranged within the stent, and
a sealing skirt for reduction or prevention of paravalvular leakage;
wherein, in the expanded state, the sealing skirt comprises a tubular inner wall and a pocket which is positioned on the tubular inner wall and comprises an outer wall which extends radially outward from the tubular inner wall, the outer wall comprising:
a first axial end connected to the tubular inner wall and disposed toward the axial inflow end, and
a second axial end disposed towards the axial outflow end;
wherein the pocket is configured to be distended radially outward in response to inflow of blood in the expanded state; and
wherein, in the expanded state, the outer wall of the pocket comprises one or more pre-shaped bulges which extend radially outward from the outer wall of the pocket, wherein the one or more pre-shaped bulges are disposed between the first axial end and the axial outflow end of the stent.