| CPC A61B 17/1285 (2013.01) [A61B 17/12036 (2013.01); A61B 17/12122 (2013.01); A61B 17/122 (2013.01); A61B 17/1227 (2013.01); A61B 17/30 (2013.01); A61N 1/395 (2013.01); A61N 1/3968 (2013.01); B21F 45/008 (2013.01); B29C 65/08 (2013.01); B29C 66/1122 (2013.01); B29C 66/729 (2013.01); B29C 66/87445 (2013.01); A61B 2017/00243 (2013.01); A61B 2017/00371 (2013.01); A61B 2017/00526 (2013.01); A61B 2017/00632 (2013.01); A61B 2017/00831 (2013.01); A61B 2017/00946 (2013.01); A61B 2017/2926 (2013.01); B29K 2667/003 (2013.01); B29K 2995/0056 (2013.01); B29L 2031/753 (2013.01)] | 31 Claims |

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1. An application instrument comprising:
an end effector comprising
a head configured to be disposed distally on a shaft,
a stationary jaw fixedly disposed on the head and configured to releasably couple to a first clamping portion of an exclusion device for an anatomical structure, the exclusion device being biased in a closing direction, and
a movable jaw movably disposed on the head and configured to releasably couple to a second clamping portion of the exclusion device,
wherein the movable jaw is movable relative to the stationary jaw to reconfigure the exclusion device from a closed configuration to an open configuration,
wherein the end effector comprises a cover secured to the head, and
wherein the movable jaw is oriented generally parallel to the stationary jaw when the exclusion device is in the open configuration and the closed configuration.
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