US 12,478,285 B2
Accelerometer signal change as a measure of patient functional status
Bruce D. Gunderson, Plymouth, MN (US); and Ya-Jian Cheng, Lino Lakes, MN (US)
Assigned to Medtronic, Inc., Minneapolis, MN (US)
Filed by Medtronic, Inc., Minneapolis, MN (US)
Filed on May 25, 2017, as Appl. No. 15/605,100.
Claims priority of provisional application 62/370,138, filed on Aug. 2, 2016.
Prior Publication US 2018/0035924 A1, Feb. 8, 2018
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/352 (2021.01); A61B 5/00 (2006.01); A61B 5/11 (2006.01); A61B 5/364 (2021.01); A61N 1/365 (2006.01); A61N 1/37 (2006.01); A61N 1/39 (2006.01)
CPC A61B 5/1116 (2013.01) [A61B 5/352 (2021.01); A61B 5/364 (2021.01); A61B 5/686 (2013.01); A61N 1/36521 (2013.01); A61N 1/36542 (2013.01); A61N 1/36564 (2013.01); A61N 1/36592 (2013.01); A61N 1/3704 (2013.01); A61N 1/3925 (2013.01); A61N 1/3962 (2013.01); A61B 2560/0209 (2013.01); A61B 2562/0219 (2013.01)] 22 Claims
OG exemplary drawing
 
1. An implantable medical device (IMD) system comprising:
an implantable medical device configured to be implanted in a patient, the implantable medical device comprising:
communication circuitry configured to establish a communication link and transfer data between the IMD intra-corpus and a computing device extra-corpus; and
accelerometer circuitry configured to generate a plurality of accelerometer signals including a sagittal axis accelerometer signal, a vertical axis accelerometer signal, and a transverse axis accelerometer signal, wherein the sagittal axis accelerometer signal indicates an acceleration along a sagittal axis, wherein the vertical axis accelerometer signal indicates an acceleration along a vertical axis, wherein the transverse axis accelerometer signal indicates an acceleration along a transverse axis, and wherein the sagittal axis, the vertical axis, and the transverse axis represent three axes of a cartesian coordinate system; and
processing circuitry configured to:
calculate, based on at least one accelerometer signal of the plurality of accelerometer signals, a patient-specific functional status parameter value associated with each sit-to-stand test of a set of sit-to-stand tests, wherein the set of sit-to-stand tests includes a plurality of pairs of consecutive sit-to-stand tests;
identify a set of difference metric values, wherein each difference metric value of the set of difference metric values corresponds to a respective pair of consecutive sit-to-stand tests of the plurality of pairs of consecutive sit-to-stand tests,
wherein each difference metric value of the set of difference metric values represents a difference between the patient-specific functional status parameter value associated with a first sit-to-stand test of the respective pair of consecutive sit-to-stand tests and the patient-specific functional status parameter of a second sit-to-stand test of the respective pair of consecutive sit-to-stand tests, wherein the first sit-to-stand test occurs after the second sit-to-stand test;
calculate a score based on the set of difference metric values;
determine, based on the score, a patient functional status associated with the patient;
store the patient functional status in a dataset comprising a set of patient functional statuses, wherein each patient functional status of the set of patient functional statuses comprises a timestamp corresponding to a portion of the plurality of accelerometer signals used to determine the patient functional status;
control the communication circuitry to transmit, from the IMD to the computing device, an indication of the patient functional status;
control the communication circuitry to receive, by the IMD system from the computing device and based on the indication of the patient functional status, one or more updated therapy parameters for use in delivering therapy to the patient; and
control therapy delivery circuitry to deliver therapy to the patient according to the one or more updated therapy parameters.