US 12,478,276 B2
System for time-series analysis of fluorescence blood flow and method thereof
Te-I Chang, Taipei (TW); Rui-Cian Weng, Taipei (TW); and Yen-Pei Lu, Taipei (TW)
Assigned to Taipei Medical University, Taipei (TW)
Filed by Taipei Medical University, Taipei (TW)
Filed on Apr. 11, 2024, as Appl. No. 18/632,394.
Claims priority of application No. 112146926 (TW), filed on Dec. 1, 2023.
Prior Publication US 2025/0176849 A1, Jun. 5, 2025
Int. Cl. A61B 5/00 (2006.01); A61B 5/0275 (2006.01)
CPC A61B 5/0275 (2013.01) [A61B 5/0071 (2013.01); A61B 5/681 (2013.01); A61B 5/6828 (2013.01); A61B 5/6831 (2013.01); A61B 2560/0462 (2013.01); A61B 2562/0233 (2013.01); A61B 2562/164 (2013.01); A61B 2562/185 (2013.01)] 2 Claims
OG exemplary drawing
 
1. A movable fluorescent blood flow monitoring device selectively fixed at a proximal or distal end of a human body, comprising:
a main body with a darkroom space, wherein the darkroom space is made of flexible material surrounding the main body and forming an open side to conform to the skin of the proximal or distal end of the human body;
a fixation device positioned on the side of the main body in the form of an elastic strap, for securing the fluorescent blood flow monitoring device to the proximal or distal end of the human body;
a detection device positioned on the side of the darkroom space away from the proximal or distal end of the human body, further comprising at least two near-infrared LED light sources and a filter receiver; wherein the near-infrared LED light sources are configured to illuminate the skin of the proximal or distal end of the human body to excite fluorescent dye in the blood, and the filter receiver is configured to obtain a fluorescent contrast agent signal by passing fluorescence having a wavelength of 800 nm to 850 nm while blocking light of other wavelengths;
a transmission device positioned within the main body, and electrically connected to the detection device, comprising a wireless communication unit, the wireless communication unit being configured to transmit the fluorescent contrast agent signal to a processing device via wireless communication; and
a battery unit positioned within the main body, providing power to the detection device and the transmission device.