US 12,148,519 B2
Apparatuses and methods for modelling and control of ice formation during cryoablation treatments
Hongxuan Zhang, Austin, TX (US)
Assigned to Varian Medical Systems, Inc., Palo Alto, CA (US)
Filed by Varian Medical Systems, Inc., Palo Alto, CA (US)
Filed on May 20, 2022, as Appl. No. 17/664,228.
Prior Publication US 2023/0377713 A1, Nov. 23, 2023
Int. Cl. G16H 20/40 (2018.01)
CPC G16H 20/40 (2018.01) 20 Claims
OG exemplary drawing
 
1. A system for performing a cryoablation treatment comprising at least one computing device, the at least one computing device configured to:
obtain an ice formation model;
prepare a cryoablation treatment plan based on the ice formation model and one or more characteristics of the target tissue;
initiate a cryoablation freezing cycle;
obtain ice formation data that describes one or more characteristics of ice being formed during the cryoablation freezing cycle;
determine a position of one or more isotherms of the ice being formed based on the ice formation data and the ice formation model;
compare the ice formation data to the ice formation model to determine whether the ice being formed during the cryoablation treatment is growing in a predicted manner using one or more affine ratios; and
adjust growth of the ice being formed by adjusting a flow of cryogen to a cryoprobe when the ice formation data indicates that the one or more affine ratios are greater than a predetermined upper threshold or less than a predetermined lower threshold.