US 12,148,159 B2
Systems and methods to process electronic images to produce a tissue map visualization
Jason Locke, Westport, CT (US); Jillian Sue, New York, NY (US); Christopher Kanan, Pittsford, NY (US); and Sese Ih, New York, NY (US)
Assigned to Paige.AI, Inc., New York, NY (US)
Filed by PAIGE.AI, Inc., New York, NY (US)
Filed on Dec. 6, 2023, as Appl. No. 18/530,844.
Application 18/530,844 is a continuation of application No. 17/655,524, filed on Mar. 18, 2022, granted, now 11,887,304.
Application 17/655,524 is a continuation of application No. 17/350,328, filed on Jun. 17, 2021, granted, now 11,315,249, issued on Apr. 26, 2022.
Claims priority of provisional application 63/041,778, filed on Jun. 19, 2020.
Prior Publication US 2024/0112338 A1, Apr. 4, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. G06K 9/00 (2022.01); A61B 6/00 (2024.01); G06N 20/00 (2019.01); G06T 3/40 (2006.01); G06T 7/00 (2017.01); G06T 11/60 (2006.01); G16H 10/40 (2018.01); G16H 30/40 (2018.01); G16H 70/60 (2018.01)
CPC G06T 7/0012 (2013.01) [G06N 20/00 (2019.01); G06T 3/40 (2013.01); G06T 11/60 (2013.01); G16H 10/40 (2018.01); G16H 30/40 (2018.01); G16H 70/60 (2018.01); G06T 2207/20081 (2013.01); G06T 2207/30024 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A computer-implemented method for analyzing an image of a slide corresponding to a specimen, the method comprising:
receiving at least one digitized image of a pathology specimen;
determining, using the digitized image at an artificial intelligence (AI) system, at least one salient feature, the at least one salient feature comprising a biomarker, cancer, cancer grade, parasite, toxicity, inflammation, and/or cancer sub-type;
determining, at the AI system, a salient region overlay for the digitized image, wherein the AI system indicates a value for each pixel;
representing the salient region overlay by a set of super-pixels associated with a score, the score being associated with the at least one salient feature being present or absent;
suppressing, based on the value for each pixel, one or more non-salient regions of the digitized image; and
converting the salient region overlay into a tissue map.