US 12,148,070 B2
Dead-time correction method in quantitative positron emission tomography (PET) reconstruction for various objects and radioactivity distributions
Xiyun Song, San Jose, CA (US); Jinghan Ye, Livermore, CA (US); Yanfei Mao, Highland Heights, OH (US); Chuanyong Bai, Solon, OH (US); Andriy Andreyev, Willoughby Hills, OH (US); Gregory Doughty, Beachwood, OH (US); Leonid Romanov, Mayfield Heights, OH (US); and Zhiqiang Hu, Twinsburg, OH (US)
Assigned to KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
Appl. No. 16/963,307
Filed by KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
PCT Filed Jan. 24, 2019, PCT No. PCT/EP2019/051709
§ 371(c)(1), (2) Date Jul. 20, 2020,
PCT Pub. No. WO2019/145398, PCT Pub. Date Aug. 1, 2019.
Claims priority of provisional application 62/622,413, filed on Jan. 26, 2018.
Prior Publication US 2021/0366165 A1, Nov. 25, 2021
Int. Cl. G01T 1/161 (2006.01); A61B 5/00 (2006.01); G01T 1/164 (2006.01); G01T 1/17 (2006.01); G01T 1/20 (2006.01); G06T 11/00 (2006.01)
CPC G06T 11/005 (2013.01) [G01T 1/161 (2013.01); G01T 1/164 (2013.01); G01T 1/171 (2013.01); A61B 5/00 (2013.01); G01T 1/20 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A non-transitory computer-readable medium storing instructions readable and executable by a workstation including at least one electronic processor to perform an image reconstruction method, the method comprising:
determining singles rates of a plurality of radiation detectors in a frame of imaging data detected by the radiation detectors;
determining an energy correction factor (Nwgt) for each radiation detector based on an energy spectrum distribution of gamma rays incident on the radiation detector during acquisition of the frame of imaging data;
determining a singles live time correction factor for each radiation detector from the singles rate and the energy correction factor determined for the radiation detector;
for each line of response (LOR) of a plurality of LORs connecting pairs of radiation detectors, determining a live time correction factor for the LOR from the determined singles live time correction factors of the pair of radiation detectors connected by the LOR; and
reconstructing the frame of imaging data using the determined LOR live time correction factors.