| CPC G05B 19/404 (2013.01) [G06N 20/00 (2019.01); G05B 2219/37506 (2013.01)] | 20 Claims |

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1. A method, comprising:
receiving first sensor data, generated during a manufacturing process by sensors associated with a substrate manufacturing chamber;
receiving simulated sensor data generated by a trained physics-based model;
determining that an actuator of the substrate manufacturing chamber contributes to a difference between the first sensor data and the simulated sensor data, by determining that a difference between first data indicative of chamber pressure and second data indicative of chamber pressure is less than a first threshold value; and
causing performance of a corrective action in view of the difference between the first sensor data and the simulated sensor data.
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