| CPC B01D 15/22 (2013.01) [B01D 15/363 (2013.01); G01N 30/06 (2013.01)] | 12 Claims |

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1. A chromatography device comprising:
an upper housing having an inlet;
a lower housing having an outlet;
the upper and lower housings ultrasonically welded together forming a housing by an interlocking weld extension having a chamfered tip located on either the upper housing or the lower housing and an opposing step located on either the lower housing or the upper housing opposite the interlocking weld extension;
a housing longitudinal axis through the housing;
a compression extension located on either the upper housing or the lower housing positioned closer to the longitudinal axis than the interlocking weld extension and an opposing boss located on either the lower housing or the upper housing opposite the compression extension; and
a media disposed between the compression extension and the boss such that a perimeter of the media is compressed between the compression extension and the boss forming a liquid impermeable seal along the perimeter after the upper housing is ultrasonically welded to the lower housing.
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