US 12,144,963 B2
Image-guided lumbar puncture aspiration and injector system and method
Deep Arjun Singh, Cambridge, MA (US); and P J Anand, Lowell, MA (US)
Assigned to ALCYONE THERAPEUTICS, INC., Lowell, MA (US)
Filed by ALCYONE THERAPEUTICS, INC., Lowell, MA (US)
Filed on Jul. 17, 2020, as Appl. No. 16/932,307.
Claims priority of provisional application 62/893,630, filed on Aug. 29, 2019.
Claims priority of provisional application 62/875,463, filed on Jul. 17, 2019.
Prior Publication US 2021/0016000 A1, Jan. 21, 2021
Int. Cl. A61M 5/172 (2006.01); A61B 17/34 (2006.01); A61M 5/19 (2006.01); A61M 5/20 (2006.01); A61M 5/32 (2006.01); A61M 5/34 (2006.01); A61B 90/00 (2016.01)
CPC A61M 5/172 (2013.01) [A61B 17/3403 (2013.01); A61M 5/19 (2013.01); A61M 5/20 (2013.01); A61M 5/3293 (2013.01); A61M 5/3297 (2013.01); A61M 5/34 (2013.01); A61B 2017/3413 (2013.01); A61B 2090/378 (2016.02); A61M 2205/3303 (2013.01); A61M 2205/3331 (2013.01); A61M 2205/52 (2013.01); A61M 2205/582 (2013.01); A61M 2210/1003 (2013.01); A61M 2230/06 (2013.01); A61M 2230/42 (2013.01)] 7 Claims
OG exemplary drawing
 
1. An image-guided aspiration and injector system, comprising:
an auto-injection device having a housing, at least one syringe carried by the housing and having a fluid and a portion extending outside the housing, and a controller disposed within the housing;
an imaging device coupled to the auto-injection device and adapted to capture at least one image of a puncture area of a patient;
a needle assembly coupled to the portion of the at least one syringe of the auto-injection device extending outside the housing and including a needle adapted to be inserted into a dura of the patient; and
a needle guide having a base and a body extending from the base, the base adapted to be disposed on the puncture area, and the body having an aperture for receiving the needle of the needle assembly,
wherein, after the needle is inserted into the aperture of the needle guide and into a location of the puncture area identified by the imaging device, the controller is configured to retrieve an infusion and aspiration profile, the infusion and aspiration profile comprising an infusion and aspiration protocol for the at least one syringe, the controller configured to operate the auto-injection device based on the infusion and aspiration protocol, and
wherein the body of the needle guide is cone-shaped and extends upwardly from the base of the needle guide, the body having a first end including the aperture for receiving the needle and a second end disposed opposite the first end, the second end adjacent to the base, and the base configured to contact a portion of the puncture area and including an adhesive portion adapted to contact the puncture area.