US 12,144,842 B2
Process of preparation of glycan compositions and uses thereof
Adeyemi Adesokan, Lausanne (CH); and Jean-Philippe Kunz, Verbier (CH)
Assigned to Gnubiotics Sciences SA, Epalinges (CH)
Appl. No. 16/975,384
Filed by Gnubiotics Sciences SA, Epalinges (CH)
PCT Filed Feb. 22, 2019, PCT No. PCT/EP2019/054413
§ 371(c)(1), (2) Date Aug. 24, 2020,
PCT Pub. No. WO2019/162425, PCT Pub. Date Aug. 29, 2019.
Claims priority of application No. 18158116 (EP), filed on Feb. 22, 2018; and application No. 18182825 (EP), filed on Jul. 11, 2018.
Prior Publication US 2020/0397861 A1, Dec. 24, 2020
Int. Cl. A61K 38/17 (2006.01); A23K 20/147 (2016.01); A23K 20/163 (2016.01); A23L 33/00 (2016.01); A23L 33/125 (2016.01); A23L 33/18 (2016.01); A61K 31/715 (2006.01)
CPC A61K 38/1735 (2013.01) [A23K 20/147 (2016.05); A23K 20/163 (2016.05); A23L 33/125 (2016.08); A23L 33/18 (2016.08); A23L 33/40 (2016.08); A61K 31/715 (2013.01); A23V 2002/00 (2013.01)] 19 Claims
 
1. A composition comprising 3 or more different glycans and a ratio of glycopeptides: free glycans (w/w) between 51:33 and 51:36, wherein the glycopeptides were obtained from the hydrolysis of gastrointestinal tract mucins; and the composition is capable of promoting the growth of Akkermansia muciniphila in a mammalian gut.