	US 12,144,786 B2
	Methods of treatment for anorexia nervosa, bulimia and related clinical syndromes
Barbara Scolnick, Waban, MA (US); and Caroline Beckwith, New York, NY (US)
Assigned to Homeostasis Therapeutics LLC, Bronx, NY (US)
Filed by Homeostasis Therapeutics, Limited, Bronx, NY (US)
Filed on Mar. 29, 2021, as Appl. No. 17/216,033.
Claims priority of provisional application 63/000,786, filed on Mar. 27, 2020.
Prior Publication US 2021/0299065 A1, Sep. 30, 2021
Int. Cl. A61K 31/135 (2006.01); A23L 33/00 (2016.01); A23L 33/115 (2016.01); A23L 33/125 (2016.01); A23L 33/17 (2016.01); A61K 9/00 (2006.01); A61P 3/00 (2006.01); A61P 3/02 (2006.01)

CPC A61K 31/135 (2013.01) [A23L 33/115 (2016.08); A23L 33/125 (2016.08); A23L 33/17 (2016.08); A23L 33/30 (2016.08); A23L 33/40 (2016.08); A61K 9/0019 (2013.01); A61P 3/00 (2018.01); A61P 3/02 (2018.01); A23V 2002/00 (2013.01)]

21 Claims

1. A method of treating anorexia nervosa and related clinical syndromes in a subject in need thereof, said method comprising:

a) placing the subject on a ketogenic diet and maintaining the subject on the ketogenic diet for a period of time sufficient to cause a detectable increase in ketone levels above levels associated without a ketogenic diet; and

b) administering an effective amount of a pharmaceutical composition comprising ketamine or a pharmaceutically acceptable salt thereof, to the subject,

wherein combination of the ketogenic diet and administration of the pharmaceutical composition comprising ketamine or the pharmaceutically acceptable salt thereof, is effective to treat said anorexia nervosa in the subject.