US 12,473,664 B2
Medical sheet
Takafumi Konishi, Osaka (JP); Mitsuru Naiki, Kato (JP); Toshiko Ujita, Osaka (JP); and Hitoshi Yamamoto, Ono (JP)
Assigned to NIPPON ZOKI PHARMACEUTICAL CO., LTD., Osaka (JP)
Appl. No. 17/790,451
Filed by NIPPON ZOKI PHARMACEUTICAL CO., LTD., Osaka (JP)
PCT Filed Jan. 14, 2021, PCT No. PCT/JP2021/000985
§ 371(c)(1), (2) Date Jun. 30, 2022,
PCT Pub. No. WO2021/145362, PCT Pub. Date Jul. 22, 2021.
Claims priority of application No. 2020-000097U (JP), filed on Jan. 14, 2020; application No. 2020-004189 (JP), filed on Jan. 15, 2020; application No. 2020-000615U (JP), filed on Feb. 25, 2020; and application No. 2020-029404 (JP), filed on Feb. 25, 2020.
Prior Publication US 2023/0066066 A1, Mar. 2, 2023
Int. Cl. D01F 6/92 (2006.01); A61K 9/70 (2006.01); A61K 31/714 (2006.01); A61K 45/06 (2006.01); A61L 27/18 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); A61L 31/06 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); A61P 25/00 (2006.01); D01F 6/62 (2006.01)
CPC D01F 6/92 (2013.01) [D01F 6/625 (2013.01); A61K 9/70 (2013.01); A61K 9/7007 (2013.01); A61K 31/714 (2013.01); A61K 45/06 (2013.01); A61L 27/18 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61L 31/06 (2013.01); A61L 31/146 (2013.01); A61L 31/16 (2013.01); A61L 2300/428 (2013.01); A61L 2300/604 (2013.01); A61L 2430/32 (2013.01); A61P 25/00 (2018.01)] 18 Claims
OG exemplary drawing
 
1. A sheet comprising a nonwoven fabric formed of fiber containing a biodegradable aliphatic polyester, wherein a porosity of the sheet is 50 to 80% and the sheet has a cell infiltration suppressing action,
wherein a thickness of the sheet is 30 to 70 μm,
wherein the biodegradable aliphatic polyester contained in the fiber has a molecular weight distribution in which a maximum value exists in at least two or more regions of the molecular weight,
wherein the sheet further contains a drug, and
wherein a density of the sheet is 200 to 800 mg/cm3.