US 12,473,561 B2
Method of overexpressing target gene using electromagnetic wave-reactive promoter
Jongpil Kim, Seoul (KR); and Junsang Yoo, Seoul (KR)
Assigned to DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Seoul (KR)
Appl. No. 17/285,430
Filed by DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Seoul (KR)
PCT Filed Dec. 13, 2019, PCT No. PCT/KR2019/017747
§ 371(c)(1), (2) Date Apr. 14, 2021,
PCT Pub. No. WO2020/080920, PCT Pub. Date Apr. 23, 2020.
Prior Publication US 2023/0059930 A1, Feb. 23, 2023
Int. Cl. C12N 15/67 (2006.01); A61K 35/30 (2015.01); A61K 35/32 (2015.01); A61P 19/00 (2006.01); A61P 25/00 (2006.01); C12N 13/00 (2006.01)
CPC C12N 15/67 (2013.01) [A61K 35/30 (2013.01); A61K 35/32 (2013.01); A61P 19/00 (2018.01); A61P 25/00 (2018.01); C12N 13/00 (2013.01)] 2 Claims
 
1. A method of overexpressing a target gene, the method comprising steps of:
(a) introducing a vector into cells, into which vector a promoter and a target gene are inserted; and
(b) applying an electromagnetic wave of a frequency of a range from 50 Hz to 300 Hz to the cells obtained in the step (a), wherein the promoter is IFI44 promoter.