US 12,473,526 B2
Cell culture control device, cell culture device provided with same, cell culture control method, and cell culture control program
Satoshi Fukumoto, Ehime (JP); Keisuke Taira, Ehime (JP); Shougo Fukushima, Osaka (JP); and Tomoyoshi Tokumaru, Ehime (JP)
Assigned to PHC HOLDINGS CORPORATION, Tokyo (JP)
Filed by PHC Holdings Corporation, Tokyo (JP)
Filed on Jan. 31, 2023, as Appl. No. 18/103,960.
Application 18/103,960 is a continuation of application No. PCT/JP2021/046057, filed on Dec. 14, 2021.
Claims priority of application No. 2021-014583 (JP), filed on Feb. 1, 2021.
Prior Publication US 2023/0174920 A1, Jun. 8, 2023
Int. Cl. C12M 1/36 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01)
CPC C12M 41/48 (2013.01) [C12M 29/06 (2013.01); C12M 41/32 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A cell culture control device, comprising:
a consumption amount information acquisition unit configured to acquire an amount of consumed nutrients from a result of continuously measuring a concentration of nutrients contained in a culture medium contained in a culture vessel;
a consumption rate calculation unit configured to differentiate the amount of consumed nutrients acquired by the consumption amount information acquisition unit, and calculates the consumption rate at which the nutrients are consumed;
a culture medium replacement detection unit configured to detect that the culture medium contained in the culture vessel has been replaced or added; and
a next step transition determination unit configured to determine whether or not to proceed to a next step according to whether or not the consumption rate after replacement or addition of the culture medium calculated by the consumption rate calculation unit satisfies a specific condition when the culture medium replacement detection unit detects that the culture medium has been replaced or added.