US 12,473,264 B2
Inhibitors of erythrocyte band 3 tyrosine phosphorylation and uses thereof
Philip Stewart Low, West Lafayette, IN (US); Daniel A. Sheik, Lafayette, IN (US); and Som Dutt, Shamli Uttar (IN)
Assigned to Purdue Research Foundation, West Lafayette, IN (US)
Appl. No. 17/620,043
Filed by Purdue Research Foundation, West Lafayette, IN (US)
PCT Filed Jun. 18, 2020, PCT No. PCT/US2020/038491
§ 371(c)(1), (2) Date Dec. 16, 2021,
PCT Pub. No. WO2020/257495, PCT Pub. Date Dec. 24, 2020.
Claims priority of provisional application 62/862,743, filed on Jun. 18, 2019.
Prior Publication US 2022/0388968 A1, Dec. 8, 2022
Int. Cl. C07D 403/12 (2006.01); A61P 7/06 (2006.01); C07D 239/48 (2006.01)
CPC C07D 239/48 (2013.01) [A61P 7/06 (2018.01); C07D 403/12 (2013.01)] 8 Claims
 
1. A compound of formula (I):

OG Complex Work Unit Chemistry
wherein:
R1 is substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
R2 is halogen; and
R3 is

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.