US 12,472,387 B2
Accelerating cutaneous healing utilizing non-invasive focused ultrasound
Christine A. Morton, Mechanicville, NY (US); Christopher Michael Puleo, Niskayuna, NY (US); Jeffrey Michael Ashe, Gloversville, NY (US); and Victoria Eugenia Cotero, Troy, NY (US)
Assigned to GE PRECISION HEALTHCARE LLC, Waukesha, WI (US)
Filed by General Electric Company, Schenectady, NY (US)
Filed on Oct. 5, 2023, as Appl. No. 18/481,700.
Claims priority of provisional application 63/413,365, filed on Oct. 5, 2022.
Prior Publication US 2024/0115886 A1, Apr. 11, 2024
Int. Cl. A61N 7/02 (2006.01); A61N 7/00 (2006.01)
CPC A61N 7/02 (2013.01) [A61N 2007/0017 (2013.01); A61N 2007/0026 (2013.01); A61N 2007/0047 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method of promoting cutaneous wound healing, comprising:
positioning an ultrasound transducer at a stimulation site on a subject having a cutaneous wound;
non-invasively applying pulsed focused ultrasound (pFUS) using the transducer to cause modulation of a target anatomic site that is on or within an internal organ, wherein the target anatomic site contains or regulates resident or circulating immune cells; and
wherein modulation of the target anatomic site of the subject causes migration of one or more of monocytes, macrophages, or neutrophils to a wound bed of the cutaneous wound.