| CPC A61N 1/39622 (2017.08) [A61N 1/05 (2013.01); A61N 1/3956 (2013.01)] | 20 Claims |

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1. An implantable cardioverter-defibrillator (ICD) system comprising:
an ICD;
an implantable medical electrical lead that includes:
an elongated lead body having a proximal end and a distal portion;
a connector at the proximal end of the lead body configured to couple to the ICD; and
three or more electrodes along the distal portion of the elongated lead body, wherein the three or more electrodes includes a defibrillation electrode, a first sensing electrode and a second sensing electrode, the defibrillation electrode being positioned between the first sensing electrode and the second sensing electrode, and
wherein the distal portion of the elongated lead body of the lead is configured to be positioned within a substernal space of a patient and the ICD is configured to deliver electrical stimulation to a heart of the patient from the ICD using at least one of the three or more electrodes along the distal portion of the elongated lead body positioned within the substernal space,
wherein the distal portion of the elongated lead body is configured to position the three or more electrodes within the substernal space such that the defibrillation electrode is located over a cardiac silhouette of a ventricle of the heart as observed via an anterior-posterior (AP) fluoroscopic view of the heart.
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