US 12,472,285 B2
Eggshell particle containing hydrogels and prepolymer compositions for biomedical applications
Gulden Camci-Unal, Boston, MA (US); and Xinchen Wu, Boston, MA (US)
Assigned to University of Massachusetts, Boston, MA (US)
Appl. No. 17/423,266
Filed by University of Massachusetts, Boston, MA (US)
PCT Filed Jan. 15, 2020, PCT No. PCT/US2020/013654
§ 371(c)(1), (2) Date Jul. 15, 2021,
PCT Pub. No. WO2020/150332, PCT Pub. Date Jul. 23, 2020.
Claims priority of provisional application 62/792,669, filed on Jan. 15, 2019.
Prior Publication US 2022/0125996 A1, Apr. 28, 2022
Int. Cl. A61L 27/48 (2006.01); A61K 35/32 (2015.01); A61L 27/52 (2006.01); A61P 19/08 (2006.01)
CPC A61L 27/48 (2013.01) [A61K 35/32 (2013.01); A61L 27/52 (2013.01); A61P 19/08 (2018.01)] 24 Claims
OG exemplary drawing
 
1. A composition comprising a crosslinked or uncrosslinked polymer in the form of a hydrogel, and micronized eggshell particles, nanosized eggshell particles or combination of micronized eggshell particles and nanosized eggshell particles and having their unmodified eggshell membranes present, the eggshell particles and the unmodified eggshell membranes are incorporated into the polymer of the hydrogel and in an amount to reinforce the hydrogel.