	US 12,472,281 B2
	Multi-layer collagen-based membrane
Barry Bartee, Lubbock, TX (US); and Evan Cain, Lubbock, TX (US)
Assigned to Osteogenics Biomedical, Inc., Lubbock, TX (US)
Filed by Osteogenics Biomedical, Inc., Lubbock, TX (US)
Filed on Dec. 10, 2021, as Appl. No. 17/547,941.
Claims priority of provisional application 63/124,469, filed on Dec. 11, 2020.
Prior Publication US 2022/0184275 A1, Jun. 16, 2022
Int. Cl. A61L 27/24 (2006.01); A61L 27/16 (2006.01); A61L 27/18 (2006.01); A61L 27/36 (2006.01); A61L 27/40 (2006.01); A61L 27/58 (2006.01)

CPC A61L 27/24 (2013.01) [A61L 27/18 (2013.01); A61L 27/3608 (2013.01); A61L 27/3695 (2013.01); A61L 2430/00 (2013.01)]

9 Claims

1. A multi-layer collagen-based membrane, comprising a bioresorbable mesh embedded between a first decellularized natural collagen-containing membrane and a second decellularized natural collagen-containing membrane, wherein the first and second decellularized natural collagen-containing membranes are cross-linked to each other by means of exposure to ultraviolet radiation in the presence of riboflavin, and the multi-layer collagen-based membrane has a peel strength at 90° of 5-250 N/m.