US 12,472,238 B2
Porcine collagen compositions and methods of use thereof
Patrick Bilbo, Plymouth, MA (US); Katherine Faria, Middleboro, MA (US); Bonnie Kathleen Mowry, Birmingham, AL (US); and Vivek Raut, Ashland, MA (US)
Assigned to Organogenesis Inc., Canton, MA (US)
Filed by Organogenesis Inc., Canton, MA (US)
Filed on Jul. 20, 2022, as Appl. No. 17/869,614.
Claims priority of provisional application 63/224,209, filed on Jul. 21, 2021.
Prior Publication US 2024/0024429 A1, Jan. 25, 2024
Int. Cl. A61K 38/39 (2006.01); A61K 45/06 (2006.01); A61L 15/44 (2006.01); A61L 26/00 (2006.01)
CPC A61K 38/39 (2013.01) [A61K 45/06 (2013.01); A61L 15/44 (2013.01); A61L 26/0066 (2013.01); A61L 2300/404 (2013.01)] 23 Claims
 
1. A sterilized micronized collagen composition for use in wound management, the composition comprising micronized particles of a Collagen Wound Matrix (CWM) having a micronized average particle size of 100 to 1000 micrometers (um) in diameter, wherein the composition comprises greater than 95% (w/w) native porcine Type I collagen, wherein the micronized particles are flakes, wherein the composition is for application to a wound, wherein the wound is an irregularly shaped wound or a tunneling wound, and wherein the micronized size of the composition allows direct contact to the entirety of the bed of the wound.