US 12,472,213 B2
Strains of Lactobacillus delbrueckii which inhibit Porphyromonas gingivalis
Linden Hu, Sharon, MA (US); and Louis Cornacchione, Cambridge, MA (US)
Assigned to Trustees of Tufts College, Boston, MA (US)
Filed by Trustees of Tufts College, Boston, MA (US)
Filed on Sep. 25, 2023, as Appl. No. 18/372,656.
Application 18/372,656 is a division of application No. 17/440,747, granted, now 11,786,565, previously published as PCT/US2020/023454, filed on Mar. 18, 2020.
Claims priority of provisional application 62/837,690, filed on Apr. 23, 2019.
Claims priority of provisional application 62/820,210, filed on Mar. 18, 2019.
Prior Publication US 2024/0131087 A1, Apr. 25, 2024
Prior Publication US 2024/0226193 A9, Jul. 11, 2024
Int. Cl. A61K 35/744 (2015.01); A61K 35/00 (2006.01); A61K 35/74 (2015.01); A61P 1/02 (2006.01); C12N 1/20 (2006.01)
CPC A61K 35/744 (2013.01) [A61K 35/74 (2013.01); A61P 1/02 (2018.01); C12N 1/205 (2021.05); A61K 2035/115 (2013.01)] 12 Claims
 
1. A genetically engineered bacterial strain, wherein the bacterial strain is engineered to overexpress a LDBND_1487 pyruvate oxidase (pox) enzyme.