US 12,472,162 B2
Ready-to-use, terminally sterile packaging for surgical antiseptic and method of use
Javad Parvizi, Gladwyne, PA (US); Peter F. Sharkey, Villanova, PA (US); Craig J. Della Valle, Chicago, IL (US); David L. Kirschman, West Carrollton, OH (US); Harry G. Brittain, Milford, NJ (US); Mayank M. Parmar, Upper Darby, PA (US); and Alan B. Miller, Jamison, PA (US)
Assigned to CAREFUSION 213, LLC
Filed by CareFusion 213, LLC, San Diego, CA (US)
Filed on Jan. 19, 2021, as Appl. No. 17/152,565.
Application 17/152,565 is a continuation in part of application No. PCT/US2019/043288, filed on Jul. 24, 2019.
Claims priority of provisional application 62/702,863, filed on Jul. 24, 2018.
Claims priority of provisional application 62/968,100, filed on Jan. 30, 2020.
Claims priority of provisional application 62/703,830, filed on Jul. 26, 2018.
Prior Publication US 2021/0137887 A1, May 13, 2021
Int. Cl. A01N 25/02 (2006.01); A61K 31/4025 (2006.01); A61K 47/02 (2006.01); A61K 47/22 (2006.01); A61L 2/00 (2006.01); A61M 35/00 (2006.01)
CPC A61K 31/4025 (2013.01) [A61K 47/02 (2013.01); A61K 47/22 (2013.01); A61L 2/0035 (2013.01); A61M 35/003 (2013.01); A61L 2202/182 (2013.01); A61L 2202/21 (2013.01)] 19 Claims
 
1. A container containing an antiseptic composition, the antiseptic composition comprising:
povidone iodine provided at a concentration above a minimum effective concentration of available iodine;
iodide provided at a concentration sufficient to maintain the concentration of povidone iodine above the minimum effective concentration of available iodine upon gamma irradiation of the antiseptic composition;
a nonionic surfactant; and
a buffered saline solution;
wherein the container comprises a headspace of less than about 25% of the volume of the container, and
wherein the container is a squirt bottle.