US 12,472,159 B2
Compositions comprising amino acids for use in the prevention and treatment of chemotherapy side effects
Paolo Luca Maria Giorgetti, Milan (IT)
Assigned to Professional Dietetics S.p.A., Milan (IT)
Appl. No. 17/792,380
Filed by Professional Dietetics S.p.A., Milan (IT)
PCT Filed Dec. 21, 2020, PCT No. PCT/IB2020/062291
§ 371(c)(1), (2) Date Jul. 12, 2022,
PCT Pub. No. WO2021/144639, PCT Pub. Date Jul. 22, 2021.
Claims priority of application No. 102020000000442 (IT), filed on Jan. 13, 2020.
Prior Publication US 2023/0067642 A1, Mar. 2, 2023
Int. Cl. A61K 31/194 (2006.01); A61K 31/198 (2006.01); A61K 31/405 (2006.01); A61K 31/4172 (2006.01); A61K 31/704 (2006.01); A61P 9/00 (2006.01)
CPC A61K 31/194 (2013.01) [A61K 31/198 (2013.01); A61K 31/405 (2013.01); A61K 31/4172 (2013.01); A61K 31/704 (2013.01); A61P 9/00 (2018.01)] 18 Claims
OG exemplary drawing
 
1. A method of treating cardiotoxicity induced by at least one chemotherapeutic agent in a subject undergoing chemotherapy, the method comprising administering to the subject a therapeutically effective amount of an active agent, said active agent containing the amino acids leucine, isoleucine, valine, threonine, lysine and citric acid, succinic acid, malic acid wherein said chemotherapeutic agent is doxorubicin.