	US 12,472,139 B2
	Method for maintaining skin corneum layer completeness, promoting hyaluronic acid production, improving skin cell mitochondrion activity and/ or promoting skin cell proliferation by using bacterial lysate of Halobacillus trueperi TCI66207
Chu-Han Huang, Taipei (TW); and Yung-Hsiang Lin, Taipei (TW)
Assigned to TCI CO., LTD., Taipei (TW)
Filed by TCI CO., LTD., Taipei (TW)
Filed on Jun. 14, 2023, as Appl. No. 18/334,392.
Application 18/334,392 is a continuation of application No. 16/932,867, filed on Jul. 20, 2020, granted, now 11,712,413.
Claims priority of provisional application 62/875,997, filed on Jul. 19, 2019.
Prior Publication US 2023/0414487 A1, Dec. 28, 2023
Int. Cl. A61K 8/99 (2017.01); A23L 33/135 (2016.01); A61P 17/00 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01); C12N 1/20 (2006.01)

CPC A61K 8/99 (2013.01) [A23L 33/135 (2016.08); A61P 17/00 (2018.01); A61Q 19/00 (2013.01); A61Q 19/007 (2013.01); A61Q 19/08 (2013.01); C12N 1/205 (2021.05)]

14 Claims

1. A method for maintaining skin corneum layer completeness and/or promoting hyaluronic acid production in a subject in need thereof, comprising administering to the subject a composition comprising bacterial lysate of a H. trueperi TC166207 strain, wherein the H. trueperi TC166207 strain is deposited in Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures under an accession number of DSM 33381.