| CPC A61B 34/30 (2016.02) [A61B 17/12136 (2013.01); A61B 17/3207 (2013.01); A61B 2017/22038 (2013.01); A61B 2034/301 (2016.02); A61B 2034/303 (2016.02); A61B 2090/08021 (2016.02)] | 10 Claims |

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1. A method of clot removal comprising:
driving a robotically controlled instrument system toward a clot within vasculature of a patient, wherein the instrument system comprises a first elongate member and a second elongate member positioned coaxially with the first elongate member, the first elongate member having a greater number of articulation cables than the second elongate member;
piercing the clot using a blunt distal tip of a third elongate member;
reducing the clot to smaller particles using a clot cutter of the third elongate member;
deploying a distal guard along a length of the third elongate member that is downstream from a location of the clot to prevent the smaller particles from being distributed downstream in the patient;
applying a pump of the second elongate member to aspirate the clot; and
capturing the clot using a retriever of the instrument system.
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