| CPC A61B 17/22 (2013.01) [A61F 2/013 (2013.01); A61M 25/0075 (2013.01); A61B 2017/00022 (2013.01); A61B 2017/00154 (2013.01); A61B 2017/22079 (2013.01); A61B 2017/22082 (2013.01); A61B 2217/007 (2013.01); A61F 2/011 (2020.05)] | 18 Claims |

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1. A thrombectomy aspiration system, comprising:
a vacuum source;
an aspiration catheter having a proximal portion, a distal end, and a lumen extending through the proximal portion to the distal end;
a vacuum line fluidically coupling the vacuum source to the aspiration catheter;
a vacuum interruption unit along the vacuum line, the vacuum interruption unit having a single contact member configured to compress the vacuum line and completely close the vacuum line thereby shutting off vacuum to the aspiration catheter by moving orthogonally to the vacuum line and to displace fluid in the aspiration catheter distally as the vacuum interruption unit compresses the vacuum line;
a sensor configured to detect the presence of a thrombus in the vacuum line; and
a computer connected to the sensor, wherein the computer is configured to determine a change in vacuum in the vacuum line based on information from the sensor and cause the vacuum interruption unit to compress the vacuum line thereby shutting off vacuum to the aspiration catheter; and
wherein the distal displacement of the fluid in the aspiration catheter produces an exit flow of approximately 0.001 ml to approximately 1.0 ml.
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