| CPC A61B 17/22 (2013.01) [A61B 2017/00022 (2013.01); A61B 2017/00154 (2013.01); A61B 2017/00292 (2013.01); A61B 2017/00544 (2013.01); A61B 2017/22079 (2013.01)] | 25 Claims |

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1. An aspiration thrombectomy system, comprising:
a vacuum source;
a catheter including a catheter lumen having a proximal end and a distal end;
a manifold having a manifold input fluidically connected to the proximal end of the catheter lumen and a manifold output;
a sensor to detect flow through the manifold and produce a signal indicative of the detected flow;
a vacuum valve having a vacuum valve input fluidically connected to the manifold output and a vacuum valve output fluidically connected to the vacuum source; and
a controller to receive the signal indicative of the detected flow and modulate the vacuum valve based on the signal, the controller having a plurality of states including an idle state in which the vacuum valve is held only partially open for a period of time and at least one aspiration state in which the vacuum valve is fully open;
wherein the controller is in the idle state in response to the signal indicating the detected flow is open flow, and wherein the controller transitions from the idle state to an aspiration state of the at least one aspiration state in response to the signal indicating a clot or thrombus is detected.
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