| CPC A61B 6/504 (2013.01) [A61B 6/481 (2013.01); A61B 6/485 (2013.01); G06T 7/0012 (2013.01); G06T 2207/30101 (2013.01)] | 20 Claims |

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1. Computer-implemented dynamic vessel roadmapping method, comprising the steps of:
generating a vessel roadmap library, the vessel roadmap library including a plurality of vessel roadmaps, wherein each vessel roadmap comprises a vessel roadmap image and first and second alignment data, wherein the first alignment data include an alignment electrocardiogram (ECG) and wherein the second alignment data include an alignment ECG derived respiratory (EDR) signal and contrast application object segmentation data;
obtaining a real-time fluoroscopy image and corresponding real-time first and second fluoroscopy information, wherein the real-time first fluoroscopy information includes a fluoroscopy ECG and wherein the real-time second fluoroscopy information includes a fluoroscopy EDR signal and fluoroscopy object segmentation data;
overlaying a vessel roadmap image of the vessel roadmap library with the real-time fluoroscopy image based on the first alignment data, the second alignment data, and the real time first and second fluoroscopy information, wherein overlaying the vessel roadmap image comprises selecting the vessel roadmap from the roadmap library based on comparing each alignment ECG of each vessel roadmap with the fluoroscopy ECG and based on comparing each alignment EDR signal of each vessel roadmap with each fluoroscopy EDR signal; and
aligning the vessel roadmap image and the real-time fluoroscopy image based on the contrast application object segmentation data and the fluoroscopy object segmentation data,
wherein the second alignment data is derived from the corresponding vessel roadmap image.
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