US 12,471,796 B2
Method for assessing and/or reducing artifacts arising from reconstruction of MPI image data and system for visual representation of MPI image data
Jorge Chacon-Caldera, Mannheim (DE); and Jochen Franke, Karlsruhe (DE)
Assigned to Bruker BioSpin MRI GmbH, Ettlingen (DE)
Filed by Bruker BioSpin MRI GmbH, Ettlingen (DE)
Filed on Jul. 28, 2023, as Appl. No. 18/360,982.
Claims priority of application No. 22188179 (EP), filed on Aug. 1, 2022.
Prior Publication US 2024/0032813 A1, Feb. 1, 2024
Int. Cl. A61B 5/0515 (2021.01); G01R 33/12 (2006.01); G06T 5/50 (2006.01); G06T 11/00 (2006.01)
CPC A61B 5/0515 (2013.01) [G01R 33/1276 (2013.01); G06T 5/50 (2013.01); G06T 11/008 (2013.01); G06T 2207/20224 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A method for reducing artifacts arising from reconstruction of a magnetic particle imaging (MPI) total image data set (c(r)) from MPI signal data, the method comprising:
a1) providing MPI signal data (s(f), u(t)) acquired from a sample using an MPI apparatus;
a2) reconstructing signal data (s(f), u(t)) by means of an appended system matrix (SM_AB) derived from at least two system matrices (SM_A, SM_B) for generating input image data (cin(r)),
b) selecting at least one voxel as selected voxel from the input image data (cin(r)) for generating output image data (cout(r)),
c) determining eigen-reconstruction signal data sen(f) by selecting at least one line entry of the appended system matrix (SM_AB) which corresponds to the at least one selected voxel,
d) reconstructing the eigen-reconstruction signal data sen(f) using the appended system matrix (SM_AB) for generating eigen-reconstruction image data ce(r),
e) subtracting the eigen-reconstruction image data ce(r) or weighted eigen-reconstruction image data ce′(r) from the input image data cin(r) for generating updated input image data cinn′(r);
f) repeating steps b)-e) until a termination condition is met, wherein in step b) the selection is made from the updated input image data cinn′(r) and wherein at least one selected voxel is added to the output image data cout(r); and
g) outputting, after the termination condition is met, the output image data cout(r) to a display device.