US 12,142,361 B2
Methods and systems for quantitative colorimetric capnometry
Leslie E. Mace, Bend, OR (US); Elizabeth K. Siegelman, Palo Alto, CA (US); Debra L. Reisenthel, Pleasanton, CA (US); and Simon W. H. Thomas, Danville, CA (US)
Assigned to Freespira, Inc., Kirkland, WA (US)
Filed by FREESPIRA, INC., Kirkland, WA (US)
Filed on May 11, 2022, as Appl. No. 17/742,271.
Application 16/050,340 is a division of application No. 14/902,075, granted, now 10,175,254, issued on Jan. 8, 2019, previously published as PCT/US2014/046803, filed on Jul. 16, 2014.
Application 17/742,271 is a continuation of application No. 16/050,340, filed on Jul. 31, 2018, granted, now 11,538,569.
Claims priority of provisional application 61/846,742, filed on Jul. 16, 2013.
Prior Publication US 2022/0270739 A1, Aug. 25, 2022
Int. Cl. A61B 5/00 (2006.01); A61B 5/08 (2006.01); A61B 5/083 (2006.01); A61B 5/103 (2006.01); A61M 21/02 (2006.01); G01N 21/78 (2006.01); G01N 33/84 (2006.01); G16H 20/30 (2018.01); G16H 20/40 (2018.01); G16H 40/40 (2018.01); G16H 40/63 (2018.01); G16H 40/67 (2018.01); G16H 50/20 (2018.01); A61B 5/097 (2006.01); A61M 16/00 (2006.01); A61M 21/00 (2006.01); G01N 21/31 (2006.01); G01N 21/77 (2006.01); H04M 1/72412 (2021.01)
CPC G16H 20/30 (2018.01) [A61B 5/0075 (2013.01); A61B 5/0816 (2013.01); A61B 5/082 (2013.01); A61B 5/0836 (2013.01); A61B 5/1032 (2013.01); A61B 5/486 (2013.01); A61B 5/7415 (2013.01); A61M 21/02 (2013.01); G01N 21/78 (2013.01); G01N 21/783 (2013.01); G01N 33/84 (2013.01); G16H 20/40 (2018.01); G16H 40/40 (2018.01); G16H 40/63 (2018.01); G16H 40/67 (2018.01); G16H 50/20 (2018.01); A61B 5/097 (2013.01); A61B 5/4836 (2013.01); A61B 2560/0223 (2013.01); A61M 16/0051 (2013.01); A61M 16/024 (2017.08); A61M 2021/0027 (2013.01); A61M 2021/0088 (2013.01); A61M 2205/3303 (2013.01); A61M 2205/581 (2013.01); A61M 2205/582 (2013.01); A61M 2230/432 (2013.01); G01N 21/3151 (2013.01); G01N 2021/7773 (2013.01); G01N 2201/0231 (2013.01); G01N 2201/062 (2013.01); G01N 2201/1211 (2013.01); H04M 1/72412 (2021.01)] 10 Claims
OG exemplary drawing
 
1. A method for treating a user with PTSD, the method comprising:
measuring a user's baseline end-tidal CO2 level and breathing rate using a sample tube assembly and sensing unit optically coupled via a light guide to a quantitative colorimetric carbon dioxide system comprising a temperature-controlled colorimetric indicator configured to reflect light;
controlling, via a temperature controller, a temperature of the temperature-controlled colorimetric indicator to a pre-determined temperature;
generating a measurement signal pursuant to detecting the reflected light;
measuring the user's end-tidal CO2 level and breathing rate based on the measurement signal;
providing a target end-tidal CO2 level and a target breathing rate for the user;
outputting a set of tone patterns with instructions to modify the user's end-tidal CO2 level and breathing rate from an audio device during a first time period and discontinuing the output of the set of tone patterns during a second time period, wherein the tone patterns are configured to guide a breathing pattern of the user to achieve the target end-tidal CO2 level and target breathing rate; and
instructing the user to use the tone patterns during the first time period to guide the user's breathing pattern to achieve the target end-tidal CO2 level and target breathing rate and to maintain the user's breathing pattern to achieve the target end-tidal CO2 level and target breathing rate without instruction or cues during the second time period, thereby treating the user's PTSD.