US 12,142,157 B2
Apparatus and methods for fabricating and using a simulated anatomical tissue structure
Nathan E. Fisher, Atlanta, GA (US); Chen-rei Wan, Smyrna, GA (US); and Rafael Victor Andino, Grayson, GA (US)
Assigned to Clearside Biomedical, Inc., Alpharetta, GA (US)
Filed by CLEARSIDE BIOMEDICAL, INC., Alpharetta, GA (US)
Filed on May 24, 2021, as Appl. No. 17/328,658.
Claims priority of provisional application 63/029,146, filed on May 22, 2020.
Prior Publication US 2021/0366311 A1, Nov. 25, 2021
Int. Cl. G09B 23/28 (2006.01)
CPC G09B 23/285 (2013.01) 31 Claims
OG exemplary drawing
 
1. A device to simulate an eye, comprising:
an inner layer including a base portion and having at least a partial hemispherical shape, an exterior surface of the inner layer defining a set of ridges and a set of hemi-spherical indentations between the set of ridges; and
an outer layer disposed over the inner layer, the outer layer having at least a partial hemispherical shape, the outer layer and the inner layer (1) collectively defining a gap between the inner layer and the outer layer, the gap configured to receive a fluid injectate that is injected using an injector, or (2) collectively configured to possess a potential space such that the gap is formed between the inner layer and the outer layer in response to the fluid injectate being injected by the injector between the inner layer and the outer layer;
the set of ridges being disposed between the inner layer and outer layer, and collectively with the set of hemi-spherical indentations being configured to prevent a collapse of the outer layer over the inner layer in response to receiving the fluid injectate.