US 12,141,963 B2
Systems and methods for identifying bioactive agents utilizing unbiased machine learning
Jakob Metzger, New York, NY (US); Fred Etoc, New York, NY (US); Ali Brivanlou, New York, NY (US); and Eric Siggia, New York, NY (US)
Assigned to THE ROCKEFELLER UNIVERSITY, New York, NY (US)
Appl. No. 17/282,039
Filed by THE ROCKEFELLER UNIVERSITY, New York, NY (US)
PCT Filed Oct. 4, 2019, PCT No. PCT/US2019/054826
§ 371(c)(1), (2) Date Apr. 1, 2021,
PCT Pub. No. WO2020/072977, PCT Pub. Date Apr. 9, 2020.
Claims priority of provisional application 62/741,107, filed on Oct. 4, 2018.
Prior Publication US 2021/0372994 A1, Dec. 2, 2021
Int. Cl. G06T 7/62 (2017.01); C12N 5/0735 (2010.01); G01N 1/30 (2006.01); G01N 33/50 (2006.01); G06F 18/21 (2023.01); G06F 18/214 (2023.01); G06N 3/084 (2023.01); G06T 7/00 (2017.01); G06V 10/764 (2022.01); G06V 10/82 (2022.01); G06V 20/69 (2022.01); G16B 40/00 (2019.01)
CPC G06T 7/0012 (2013.01) [C12N 5/0606 (2013.01); G01N 1/30 (2013.01); G01N 33/5014 (2013.01); G01N 33/5076 (2013.01); G06F 18/214 (2023.01); G06F 18/217 (2023.01); G06N 3/084 (2013.01); G06V 10/764 (2022.01); G06V 10/82 (2022.01); G06V 20/698 (2022.01); G16B 40/00 (2019.02); C12N 2503/02 (2013.01); C12N 2510/00 (2013.01); G06T 2200/04 (2013.01); G06T 2207/20076 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30072 (2013.01); G06V 2201/03 (2022.01)] 23 Claims
OG exemplary drawing
 
1. A method for classifying a test organoid, said method comprising the steps of:
(a) imaging a test organoid to provide an organoid image; and
(b) analyzing the organoid image with a trained neural network that has been trained to assign a classification to the test organoid, wherein the classification comprises disease phenotype or non-disease phenotype.