US 12,140,559 B2
Cell analysis using ChemFET sensor array-based systems
Wolfgang Hinz, Killingworth, CT (US); John Donohue, Southbury, CT (US); and Daniel Beacham, Eugene, OR (US)
Assigned to Life Technologies Corporation, Carlsbad, CA (US)
Filed by LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US)
Filed on Dec. 22, 2022, as Appl. No. 18/145,688.
Application 18/145,688 is a continuation of application No. 16/568,133, filed on Sep. 11, 2019, granted, now 11,567,036.
Claims priority of provisional application 62/848,842, filed on May 16, 2019.
Claims priority of provisional application 62/730,960, filed on Sep. 13, 2018.
Prior Publication US 2023/0129295 A1, Apr. 27, 2023
Int. Cl. G01N 27/414 (2006.01); C09D 189/00 (2006.01); G01N 27/28 (2006.01); G01N 27/30 (2006.01); G01N 27/407 (2006.01); G01N 33/483 (2006.01)
CPC G01N 27/4145 (2013.01) [C09D 189/00 (2013.01); G01N 27/283 (2013.01); G01N 27/30 (2013.01); G01N 27/4075 (2013.01); G01N 27/4148 (2013.01); G01N 33/4836 (2013.01)] 30 Claims
OG exemplary drawing
 
16. A method for cell imaging using a ChemFET sensor array-based system comprising:
incubating a sample of cells plated on a sensor array surface of a ChemFET sensor, wherein each cell adhered to the sensor array surface after incubation has a defined footprint on the sensor array surface;
performing an experiment on the sample of cells, wherein the ChemFET sensor array-based system is configured to output a signal for each sensor in the ChemFET sensor array during the experiment; and
displaying an electroscopic image for the experiment, wherein the electroscopic image comprises an output signal for each sensor in the ChemFET sensor array at a selected time during the experiment.