US 12,139,726 B2
Adenoviruses and methods for using adenoviruses
Michael A. Barry, Rochester, MN (US)
Assigned to MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, Rochester, MN (US)
Filed by MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, Rochester, MN (US)
Filed on Jul. 18, 2023, as Appl. No. 18/354,172.
Application 18/354,172 is a division of application No. 16/690,733, filed on Nov. 21, 2019, granted, now 11,746,334.
Claims priority of provisional application 62/770,631, filed on Nov. 21, 2018.
Prior Publication US 2023/0365943 A1, Nov. 16, 2023
Int. Cl. C12N 7/00 (2006.01); A61K 35/761 (2015.01)
CPC C12N 7/00 (2013.01) [A61K 35/761 (2013.01); C12N 2750/14122 (2013.01); C12N 2750/14132 (2013.01); C12N 2750/14143 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A recombinant adenovirus (Ad) comprising nucleic acids which encode one or more immunostimulatory polypeptides, and wherein the recombinant adenovirus (Ad) capsid hexon polypeptides are from an Ad strain Ad6 and wherein the capsid hexon polypeptides comprise at least two capsid hexon hypervariable region (HVR) polypeptides from Ad strain Ad57.