US 12,139,698 B2
Axial dispersion bioreactor (ADBR) for production of microalgae and other microorganisms
Joel L. Cuello, Tucson, AZ (US); Yaser Mehdipour, Tucson, AZ (US); Andres P. Mayol, Tucson, AZ (US); Shiwei He, Tucson, AZ (US); Chen-Han Shih, Tucson, AZ (US); and Lawrence Victor Vitug, Tucson, AZ (US)
Assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, Tucson, AZ (US)
Appl. No. 16/956,895
Filed by ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, Tucson, AZ (US)
PCT Filed Dec. 21, 2018, PCT No. PCT/US2018/067106
§ 371(c)(1), (2) Date Jun. 22, 2020,
PCT Pub. No. WO2019/126654, PCT Pub. Date Jun. 27, 2019.
Claims priority of provisional application 62/609,780, filed on Dec. 22, 2017.
Prior Publication US 2020/0318052 A1, Oct. 8, 2020
Int. Cl. C12M 1/06 (2006.01); B01J 19/00 (2006.01); C12M 1/00 (2006.01)
CPC C12M 27/02 (2013.01) [B01J 19/0066 (2013.01); C12M 27/22 (2013.01); C12M 29/06 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A bioreactor system comprising:
a. a bioreactor vessel (100) for containing a fluid, comprising one or more sidewalls (120);
b. at least one mixing plate (130) comprising a surface having a plurality of holes (140) disposed through the surface, wherein the at least one mixing plate (130) extends up to and is constrained by the one or more sidewalls (120) of the bioreactor vessel (100);
c. at least one vertical guide rod (150) configured to fit through one of the plurality of holes (140) in the at least one mixing plate (130); and
d. a mechanism (160) for moving the at least one mixing plate (130) within the bioreactor vessel,
wherein the movement of the at least one mixing plate (130) enables mixing of the fluid in the bioreactor vessel to generate a hydrodynamic flow pattern.