US 12,139,452 B2
Process for the production of retinal
Werner Bonrath, Kaiseraugst (CH); Marc-André Mueller, Kaiseraugst (CH); Bettina Wuestenberg, Kaiseraugst (CH); and Viktor Zimmermann, Kaiseraugst (CH)
Assigned to DSM IP ASSETS B.V., Heerlen (NL)
Appl. No. 17/603,184
Filed by DSM IP ASSETS B.V., Heerlen (NL)
PCT Filed Apr. 3, 2020, PCT No. PCT/EP2020/059479
§ 371(c)(1), (2) Date Oct. 12, 2021,
PCT Pub. No. WO2020/212164, PCT Pub. Date Oct. 22, 2020.
Claims priority of application No. 19169201 (EP), filed on Apr. 15, 2019.
Prior Publication US 2022/0204445 A1, Jun. 30, 2022
Int. Cl. C07C 403/08 (2006.01); C07C 403/14 (2006.01)
CPC C07C 403/14 (2013.01) [C07C 403/08 (2013.01)] 14 Claims
 
1. A process for the production of a compound of formula (I):

OG Complex Work Unit Chemistry
wherein the process comprises conducting selective dehydrogenation of a compound of formula (II):

OG Complex Work Unit Chemistry
wherein R is —CHO or —CH2OH,
wherein the selective dehydrogenation is carried out in the presence of at least one transition metal catalyst.