US 12,138,398 B2
Methods and devices for providing a stimulus to a subject to induce gamma oscillations
Li-Huei Tsai, Cambridge, MA (US); Emery Brown, Brookline, MA (US); Hannah Iaccarino, Somerville, MA (US); Anthony James Martorell, Cambridge, MA (US); and Chinnakkaruppan Adaikkan, Somerville, MA (US)
Assigned to Massachusetts Institute of Technology, Cambridge, MA (US)
Filed by Massachusetts Institute of Technology, Cambridge, MA (US)
Filed on Jun. 15, 2020, as Appl. No. 16/901,628.
Application 16/901,628 is a continuation of application No. 16/375,393, filed on Apr. 4, 2019, granted, now 10,682,490.
Application 16/375,393 is a continuation of application No. 15/360,637, filed on Nov. 23, 2016, granted, now 10,265,497, issued on Apr. 23, 2019.
Claims priority of provisional application 62/259,187, filed on Nov. 24, 2015.
Prior Publication US 2020/0316335 A1, Oct. 8, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 21/00 (2006.01); A61H 23/00 (2006.01); A61N 5/06 (2006.01)
CPC A61M 21/00 (2013.01) [A61H 23/00 (2013.01); A61N 5/062 (2013.01); A61N 5/0622 (2013.01); A61M 2021/0022 (2013.01); A61M 2021/0027 (2013.01); A61M 2021/0044 (2013.01); A61N 5/0618 (2013.01); A61N 2005/063 (2013.01); A61N 2005/0651 (2013.01); A61N 2005/0662 (2013.01)] 35 Claims
OG exemplary drawing
 
1. A method comprising:
(a) stimulating a subject with a plurality of light pulses at a pulse frequency of about 35 pulses/s to about 45 pulses/s; and
(b) reducing tau phosphorylation in the visual cortex of the subject based, at least in part, on (a).