US 12,138,396 B2
Apparatus and method for monitoring nitric oxide delivery
Craig R. Tolmie, Stoughton, WI (US); Robert Schnitman, Colchester, CT (US); Joseph J. Medicis, Syracuse, NY (US); Jim Potenziano, Binghamton, NY (US); Jaron Acker, New York, NY (US); and Jeffrey Schmidt, Oregon, WI (US)
Assigned to MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED, Dublin (IE)
Filed by Mallinckrodt Pharmaceuticals Ireland Limited, Dublin (IE)
Filed on Aug. 12, 2019, as Appl. No. 16/537,955.
Application 16/537,955 is a continuation of application No. 13/800,287, filed on Mar. 13, 2013, granted, now 10,426,913.
Application 13/800,287 is a continuation in part of application No. 13/671,057, filed on Nov. 7, 2012, granted, now 9,770,570, issued on Sep. 26, 2017.
Claims priority of provisional application 61/556,525, filed on Nov. 7, 2011.
Prior Publication US 2019/0374739 A1, Dec. 12, 2019
Int. Cl. A61M 16/12 (2006.01); A61M 16/00 (2006.01); A61M 16/06 (2006.01); A61M 16/08 (2006.01); A61M 16/10 (2006.01)
CPC A61M 16/12 (2013.01) [A61M 16/0051 (2013.01); A61M 16/024 (2017.08); A61M 2016/0039 (2013.01); A61M 16/0666 (2013.01); A61M 16/085 (2014.02); A61M 2016/102 (2013.01); A61M 2202/0275 (2013.01); A61M 2205/16 (2013.01); A61M 2205/18 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/502 (2013.01); A61M 2205/581 (2013.01); A61M 2205/583 (2013.01)] 15 Claims
OG exemplary drawing
 
1. An apparatus to deliver a therapeutic gas to a patient, the apparatus comprising:
a therapeutic gas injector module comprising:
a first inlet in fluid communication with a therapeutic gas supply providing a flow of nitric oxide at a therapeutic gas supply concentration;
a second inlet in fluid communication with a breathing gas delivery system providing a flow of a breathing gas; and
an outlet to supply a combined flow of the breathing gas and the therapeutic gas to the patient;
a control circuit including a first flow sensor to measure the flow of the breathing gas from the breathing gas delivery system, wherein the control circuit comprises a backup mode in which a known constant flow of the therapeutic gas is independent of a breathing gas flow rate, wherein when the control circuit is in the backup mode, it is operable to deliver the known constant flow of the therapeutic gas and estimate a backup dose based on the known constant flow of the therapeutic gas and the measured flow of the breathing gas, wherein the control circuit is operable to store a breathing gas flow rate history; and
a display, in communication with the control circuit, that provides the estimate of the backup dose,
wherein the display is further configured to display the breathing gas flow rate history, wherein the breathing gas flow rate history comprises a peak and/or average breathing gas flow rate for a period of time;
wherein the display is further configured to display a chart and/or graphic comprising a plurality of breathing gas flow rates and a predicted dose for each of the plurality of breathing gas flow rates.