US 12,138,349 B2
Process for spray drying a GLP-1 peptide
Ole Vangsgaard, Vaerloese (DK); and Marlene Hoerslev Hansen, Ballerup (DK)
Assigned to Novo Nordisk A/S, Bagsvaerd (DK)
Appl. No. 17/438,969
Filed by Novo Nordisk A/S, Bagsvaerd (DK)
PCT Filed Mar. 13, 2020, PCT No. PCT/EP2020/056744
§ 371(c)(1), (2) Date Sep. 14, 2021,
PCT Pub. No. WO2020/187712, PCT Pub. Date Sep. 24, 2020.
Claims priority of application No. 19163103 (EP), filed on Mar. 15, 2019.
Prior Publication US 2022/0370362 A1, Nov. 24, 2022
Int. Cl. A61K 9/16 (2006.01); A61K 38/26 (2006.01)
CPC A61K 9/1688 (2013.01) [A61K 38/26 (2013.01)] 13 Claims
 
1. A process for spray drying a feed solution, comprising introducing the feed solution into a spray dryer and introducing an atomising gas and a drying gas into the spray dryer, wherein the feed solution comprises semaglutide, and wherein the spray dryer comprises a gas heater with an inner surface comprising (i) iron and 16-18% chromium or (ii) iron, chromium, and 10-14% nickel.