	US 12,138,288 B2
	Synergistic herbal compositions for testosterone boosting
Ganga Raju Gokaraju, Vijayawada (IN); Rama Raju Gokaraju, Vijayawada (IN); Kiran Bhupathiraju, Vijayawada (IN); Trimurtulu Golakoti, Vijayawada (IN); Venkata Kanaka Ranga Raju Gokaraju, Vijayawada (IN); Venkateswarlu Somepalli, Vijayawada (IN); and Venkata Krishna Raju Alluri, Vijayawada (IN)
Assigned to LAILA NUTRACEUTICALS, Vijayawada (IN)
Appl. No. 17/054,079
Filed by LAILA NUTRACEUTICALS, Vijayawada (IN)
PCT Filed May 8, 2019, PCT No. PCT/IN2019/050361 § 371(c)(1), (2) Date Nov. 9, 2020, PCT Pub. No. WO2019/215755, PCT Pub. Date Nov. 14, 2019.
Claims priority of application No. 201841017306 (IN), filed on May 8, 2018.
Prior Publication US 2021/0236572 A1, Aug. 5, 2021
Int. Cl. A61K 36/185 (2006.01); A23L 33/105 (2016.01); A23L 33/24 (2016.01); A61K 31/522 (2006.01); A61K 31/7048 (2006.01); A61K 45/06 (2006.01); A61K 47/38 (2006.01); A61P 5/24 (2006.01)

CPC A61K 36/185 (2013.01) [A23L 33/105 (2016.08); A23L 33/24 (2016.08); A61K 31/522 (2013.01); A61K 31/7048 (2013.01); A61K 45/06 (2013.01); A61K 47/38 (2013.01); A61P 5/24 (2018.01); A61K 2236/333 (2013.01); A61K 2236/51 (2013.01)]

13 Claims

1. A synergistic herbal composition comprising a combination of:

a first ingredient comprising an ethanol or aqueous ethanol extract of a Punica granatum fruit rind; and

a second ingredient comprising an ethanol or aqueous ethanol extract of a Theobroma cacao seed;

wherein the synergistic herbal composition contains the combination in an amount effective for at least one of increasing testosterone levels, inhibiting aromatase activity, increasing mitochondrial biogenesis, and increasing mTOR activation in a patient in need thereof; and

wherein the extract of the Punica granatum fruit rind and the extract of the Theobroma cacao seed are used in a ratio of 4:1 to 1:4 by weight.