US 12,138,222 B2
Medicinal product comprising a container and an aqueous liquid containing bicarbonate
Vincent Adamo, Marly (CH); and Hervé Jean Schwebel, Mulhouse (FR)
Assigned to B. Braun Melsungen AG, Melsungen (DE)
Appl. No. 17/439,582
Filed by B. Braun Melsungen AG, Melsungen (DE)
PCT Filed Apr. 16, 2020, PCT No. PCT/EP2020/060669
§ 371(c)(1), (2) Date Sep. 15, 2021,
PCT Pub. No. WO2020/212471, PCT Pub. Date Oct. 22, 2020.
Claims priority of application No. 19170164 (EP), filed on Apr. 18, 2019.
Prior Publication US 2022/0151870 A1, May 19, 2022
Int. Cl. A61J 1/14 (2023.01); A61J 1/10 (2006.01); A61J 1/16 (2023.01)
CPC A61J 1/1468 (2015.05) [A61J 1/10 (2013.01); A61J 1/16 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A medicinal product comprising a flexible mono-chamber container and an aqueous liquid containing bicarbonate and having a physiological pH value, wherein the container comprises a first side wall and a second side wall, wherein the first side wall and the second side wall comprise a barrier material, wherein the barrier material is capable of preventing or retarding escape of carbon dioxide from the container and/or intake of carbon dioxide into the container such that a final pH-value of the aqueous liquid is maintained or substantially maintained during a shelf life of the medicinal product for at least nine months at 40° Celsius within no more than 0.2 pH-value difference from a starting pH-value.