US 12,138,071 B2
Method of treating sleep disordered breathing
Mark A. Christopherson, Shorewood, MN (US); Quan Ni, Golden Valley, MN (US); Timothy P. Herbert, Maple Grove, MN (US); and John Rondoni, Plymouth, MN (US)
Assigned to Inspire Medical Systems, Inc., Golden Valley, MN (US)
Filed by Inspire Medical Systems, Inc., Golden Valley, MN (US)
Filed on Jan. 11, 2021, as Appl. No. 17/145,733.
Application 14/597,422 is a division of application No. 13/130,287, granted, now 8,938,299, issued on Jan. 20, 2015, previously published as PCT/US2009/065165, filed on Nov. 19, 2009.
Application 17/145,733 is a continuation of application No. 15/239,057, filed on Aug. 17, 2016, granted, now 10,888,267.
Application 15/239,057 is a continuation of application No. 14/597,422, filed on Jan. 15, 2015, abandoned.
Claims priority of provisional application 61/116,149, filed on Nov. 19, 2008.
Prior Publication US 2022/0160295 A1, May 26, 2022
Int. Cl. A61B 5/00 (2006.01); A61B 5/0205 (2006.01); A61B 5/024 (2006.01); A61B 5/053 (2021.01); A61B 5/0538 (2021.01); A61B 5/08 (2006.01); A61B 5/145 (2006.01); A61N 1/36 (2006.01)
CPC A61B 5/4818 (2013.01) [A61B 5/0205 (2013.01); A61B 5/0538 (2013.01); A61B 5/0803 (2013.01); A61B 5/0809 (2013.01); A61B 5/14542 (2013.01); A61B 5/4836 (2013.01); A61B 5/686 (2013.01); A61B 5/7282 (2013.01); A61N 1/3601 (2013.01); A61B 5/024 (2013.01); A61B 5/02405 (2013.01); A61B 5/053 (2013.01); A61B 2562/0214 (2013.01); A61B 2562/0247 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A method of treating of obstructive sleep apnea comprising:
arranging a first implantable stimulation element to be in electrical stimulating relation to a first hypoglossal nerve on a first side of the body and a second implantable stimulation element to be in electrical stimulating relation to a second hypoglossal nerve on an opposite second side of the body; and
applying electrical stimulation, via the first and second implantable stimulation elements, to the respective first and second hypoglossal nerve;
automatically adjusting an intensity of the electrical stimulation of the respective first and second hypoglossal nerves within a nightly sleep treatment period according to:
a bilateral parameter to electrically stimulate one or both of the respective first and second hypoglossal nerves;
a multi-site parameter to electrically stimulate at least one of different multiple sites along a length of the first hypoglossal nerve on the first side of the body and/or at least one of different multiple sites along a length of the first hypoglossal nerve on the second side of the body; and
multi-fascicle parameter to electrically stimulate at least one of different multiple fascicles within the first hypoglossal nerve on the first side of the body and/or at least one of different multiple fascicles along the second hypoglossal nerve on the second side of the body, and
implementing the automatic adjustment via at least the bilateral parameter, the multi-site parameter, and the multi-fascicle parameter to selectively:
incrementally increase the intensity of the stimulation upon sensing sleep disordered breathing behavior exceeding a programmable threshold; and
decrementally decrease the intensity of the stimulation upon sensing sleep disordered breathing behavior below the programmable threshold.