| CPC A61B 5/0036 (2018.08) [A61B 5/0066 (2013.01); A61B 5/0084 (2013.01); A61B 10/04 (2013.01); A61B 34/37 (2016.02); A61B 2010/045 (2013.01); A61B 2017/00119 (2013.01); A61B 2034/302 (2016.02); A61B 2090/3735 (2016.02); A61M 25/0102 (2013.01)] | 20 Claims |

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1. A system for performing a minimally invasive procedure, the system comprising:
a flexible catheter with a lumen extending therethrough;
an elongate instrument sized for passage through the lumen;
an optical coherence tomographic sensor coupled to the elongate instrument; and
a control system including one or more processors, wherein the control system is configured to:
receive sensor data from the optical coherence tomographic sensor;
profile a tissue based on the received sensor data; and
determine a distance between the elongate instrument and the profiled tissue.
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