US 12,137,713 B2
Devices and methods for the preparation of a nutritional formula
Eric First, Morristown, NJ (US); David Brown, Brookline, MA (US); and Albert Archie Stone, Fuquay-Varina, NC (US)
Assigned to Alcresta Therapeutics, Inc., Waltham, MA (US)
Filed by Alcresta Therapeutics, Inc., Newton, MA (US)
Filed on Mar. 1, 2022, as Appl. No. 17/684,278.
Application 17/684,278 is a continuation of application No. 16/123,712, filed on Sep. 6, 2018, granted, now 11,291,236.
Claims priority of provisional application 62/643,394, filed on Mar. 15, 2018.
Claims priority of provisional application 62/556,700, filed on Sep. 11, 2017.
Prior Publication US 2022/0264926 A1, Aug. 25, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61J 15/00 (2006.01); A23L 29/00 (2016.01); A23L 33/12 (2016.01); A61K 38/46 (2006.01); A61K 38/47 (2006.01); A61K 38/48 (2006.01); C12N 9/20 (2006.01); C12N 9/26 (2006.01); C12N 9/50 (2006.01); A23L 33/00 (2016.01); A61J 3/00 (2006.01); A61K 9/00 (2006.01); A61M 5/14 (2006.01); A61M 5/142 (2006.01); A61M 5/168 (2006.01)
CPC A23L 29/06 (2016.08) [A23L 33/12 (2016.08); A61J 15/0026 (2013.01); A61J 15/0076 (2015.05); A61J 15/0092 (2013.01); A61K 38/465 (2013.01); A61K 38/47 (2013.01); A61K 38/48 (2013.01); C12N 9/20 (2013.01); C12N 9/2411 (2013.01); C12N 9/50 (2013.01); C12Y 301/01003 (2013.01); C12Y 302/01001 (2013.01); C12Y 304/00 (2013.01); A23L 33/40 (2016.08); A61J 3/002 (2013.01); A61K 9/0029 (2013.01); A61M 5/1409 (2013.01); A61M 5/142 (2013.01); A61M 5/16827 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A device comprising:
an inlet;
a chamber;
immobilized lipase contained within the chamber;
immobilized protease contained within the chamber;
immobilized amylase contained within the chamber; and
an outlet, wherein a flow path extends from the inlet, through the chamber, and to the outlet, so that a nutritional formula flowing through the device is exposed to the lipase, the protease, and the amylase, wherein the resulting hydrolyzed nutritional formula, upon flowing from the outlet, does not contain the immobilized lipase, the immobilized protease, or the immobilized amylase.