| CPC H04N 23/74 (2023.01) [A61B 1/00006 (2013.01); A61B 1/000096 (2022.02); A61B 1/043 (2013.01); A61B 1/045 (2013.01); A61B 1/0638 (2013.01); A61B 1/0655 (2022.02); A61B 5/0035 (2013.01); A61B 5/0086 (2013.01)] | 20 Claims |

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1. A system for endoscopic visualization in a light deficient environment, the system comprising:
an image sensor comprising a pixel array that reads out a plurality of data frames over a plurality of frame periods, wherein each of the plurality of frame periods comprises a blanking period and a readout period; and
a controller that synchronizes operations of the image sensor with a variable pulse cycle of an emitter;
wherein the controller calculates register values for an applied gain for the image sensor on a per-frame basis;
wherein the calculation of the register values for the applied gain is based at least in part on a type of a data frame of the plurality of data frames; and
wherein the controller calculates a duration of each of the plurality of frame periods on a per-frame basis.
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