| CPC G01B 11/161 (2013.01) [G01B 9/0201 (2013.01); G01B 11/18 (2013.01); G01D 5/35312 (2013.01); G01L 1/245 (2013.01); G01L 9/0079 (2013.01)] | 15 Claims |

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1. A method of optically measuring a response of a sample to a change in an environmental condition to which the sample is exposed, wherein use is made of an optical sensing device comprising:
a support with an aperture, the optical sensing device being adapted to removably hold the sample against the support around the aperture so that a portion of the sample is free to deform through the aperture; and
an optical waveguide fixedly arranged with respect to the support whereby an end of the optical waveguide faces the aperture,
the method comprising:
forming an optical interferometric cavity between, one the one hand, the end of the optical waveguide and, on the other hand, a refractive index discontinuity at a surface of the portion of the sample, which is free to protrude through the aperture, the optical interferometric cavity having an optical path length;
changing the environmental condition to which the sample is exposed so as to cause deformation of the portion of the sample through the aperture; and
measuring a variation in the optical path length of the optical interferometric cavity in response to the change in the environmental condition.
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